According to the National Safety Council, individuals who are taking opioids should:
Take as Directed
If you take an opioid prescription painkiller, over time you will feel less of the effect and need more of the medication. Do not use more without talking to your doctor. The safest use of these medications is generally at the lowest possible dose for the shortest duration. Never mix opioid medications with alcohol, sleep aids, anti-anxiety drugs or other pain relievers.